(±)-1,2-Propanediol-d6

Names

[ Name ]:
(±)-1,2-Propanediol-d6

Biological Activity

[Description]:

(±)-1,2-Propanediol-d6 is the deuterium labeled (±)-1,2-Propanediol[1]. (±)-1,2-Propanediol (1,2-(RS)-Propanediol) is an aliphatic alcohol and frequently used as an excipient in many drug formulations to increase the solubility and stability of drugs[2].

[Related Catalog]:

Research Areas >> Others

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

[2]. De Cock RF, et al. Low but inducible contribution of renal elimination to clearance of propylene glycol in preterm and term neonates. Ther Drug Monit. 2014 Jun;36(3):278-87.

Chemical & Physical Properties

[ Density]:
1.118 g/mL at 25ºC

[ Boiling Point ]:
187ºC(lit.)

[ Melting Point ]:
-60ºC(lit.)

[ Molecular Formula ]:
C₃H₂D₆O₂

[ Molecular Weight ]:
82.13140

[ Flash Point ]:
103ºC

[ Exact Mass ]:
82.09010

[ PSA ]:
40.46000

[ Storage condition ]:
2-8°C

(±)-1,2-Propanediol-d6

Names

Biological Activity

Chemical & Physical Properties

Related Compounds