H-Pro-Leu-OH

Names

[ Name ]:
H-Pro-Leu-OH

[Synonym ]:
L-prolyl-L-leucine
proline-leucine
D-prolyl-L-leucine
4-methyl-2-(pyrrolidin-2-ylcarbonylamino)pentanoic acid
Pro-leu
L-Pro-L-Leu-OH
prolyl L-leucine

Biological Activity

[Description]:

(S)-4-Methyl-2-((S)-pyrrolidine-2-carboxamido)pentanoic acid is a leucine derivative[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].

[References]

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.

Chemical & Physical Properties

[ Density]:
1.126g/cm3

[ Boiling Point ]:
457.5ºC at 760 mmHg

[ Molecular Formula ]:
C₁₁H₂₀N₂O₃

[ Molecular Weight ]:
228.28800

[ Flash Point ]:
230.5ºC

[ Exact Mass ]:
228.14700

[ PSA ]:
78.43000

[ LogP ]:
1.07360

[ Index of Refraction ]:
1.496

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Precursor & DownStream

Precursor

DownStream

Articles

Differences in signalling by directly and indirectly binding ligands in bacterial chemotaxis.

EMBO J. 29 , 3484 - 3495, (2010)

In chemotaxis of Escherichia coli and other bacteria, extracellular stimuli are perceived by transmembrane receptors that bind their ligands either directly, or indirectly through periplasmic-binding ...