lysophosphatidylcholine O-16:0/0:0

Names

[ Name ]:
lysophosphatidylcholine O-16:0/0:0

[Synonym ]:
LYSO-PAF16
Ethanaminium, 2-[[[(2R)-3-(hexadecyloxy)-2-hydroxypropoxy]hydroxyphosphinyl]oxy]-N,N,N-trimethyl-, inner salt
1-hexadecyl-sn-glycero-3-phosphocholine
1-hexadecyl
1-O-hexadecyl lyso PAF
C16 LYSO PAF
1-O-hexadecyl lyso platelet-activating factor
1-O-PALMITYL-SN-GLYCERO-3-PHOSPHOCHOLINE
lysophosphatidylcholine O-16:0/0:0
1-O-hexadecyl-2-lyso-sn-glycero-3-phosphocholine
(2R)-3-(Hexadecyloxy)-2-hydroxypropyl 2-(trimethylammonio)ethyl phosphate
1-O-hexadecyl-2-hydroxy-sn-glycero-3-phosphocholine
LYSO-PLATELET ACTIVATING FACTOR
MFCD00042932
1-alkyl-2-hydroxy-sn-glycero-3-phosphocholine
LYSO-PLATELET ACTIVATING FACTOR-16
1-Hexyldecyl-sn-glycerol-3-phosphorylcholine

Biological Activity

[Description]:

Lyso-PAF C-16 is a substrate of lysoplasmalogen (LysoPls)-specific phospholipase D (LysoPLD). Lyso-PAF C-16 selective acetylates with arachidonic acid[1][2].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Venable ME, et al. Enzymatic studies of lyso platelet-activating factor acylation in human neutrophils and changes upon stimulation. J Biol Chem. 1993 Apr 15;268(11):7965-75.

[2]. Yamaura S, et al. Novel enzymatic method for assaying Lp-PLA2 in serum. Clin Chim Acta. 2018 Jun;481:184-188.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₄H₅₂NO₆P

[ Molecular Weight ]:
481.647

[ Exact Mass ]:
481.353210

[ PSA ]:
97.86000

[ LogP ]:
3.23

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Risk Phrases ]:
R10;R21

[ Safety Phrases ]:
22-24/25

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2923900090

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2923900090

[ Summary ]:
2923900090 other quaternary ammonium salts and hydroxides。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

Articles

Metabolism of platelet-activating factor by rat alveolar macrophages: lyso-PAF as an obligatory intermediate in the formation of alkylarachidonoyl glycerophosphocholine species.

Biochim. Biophys. Acta 837 , 52, (1985)

1-Alkyl-2-acetyl-sn-glycero-3-phosphocholine (alkylacetyl-GPC; platelet-activating factor; PAF) is actively taken up and metabolized by rat alveolar macrophages maintained in culture. The major metabo...

Myocardial dysfunction and coronary vasoconstriction induced by platelet-activating factor in the post-infarcted rabbit isolated heart.

J. Mol. Cell. Cardiol. 20(6) , 547-61, (1988)

Myocardial injury was produced in separated groups of anesthetized rabbits by occlusion of the left circumflex coronary artery for 1 h followed by reperfusion for 2, 4, or 6 h after release of the occ...

Metabolism of platelet activating factor (PAF) and related ether lipids by neonatal rat myocytes.

J. Lipid Mediat. 1(2) , 113-23, (1989)

Suspensions of neonatal rat myocytes were used to investigate the metabolism of [3H]PAF (1-alkyl-2-acetyl-(sn-glycero-3-phosphocholine) (GPC] and [3H]alkyllyso-GPC. [3H]Alkylacyl-GPC consisting of mol...