Z-LEHD-FMK TFA

Names

[ Name ]:
Z-LEHD-FMK TFA

[Synonym ]:
MFCD01862609

Biological Activity

[Description]:

Z-LEHD-FMK TFA is an irreversible caspase-9 inhibitor, protects against lethal reperfusion injury and attenuate apoptosis[1][2].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Apoptosis >> Caspase

Research Areas >> Inflammation/Immunology

[Target]

Caspase-9

[References]

[1]. M M Mocanu, et al. Caspase inhibition and limitation of myocardial infarct size: protection against lethal reperfusion injury. Br J Pharmacol. 2000 May;130(2):197-200.

[2]. Graham Mouw, et al. Caspase-9 inhibition after focal cerebral ischemia improves outcome following reversible focal ischemia. Metab Brain Dis. 2002 Sep;17(3):143-51.

Chemical & Physical Properties

[ Molecular Formula ]:
C₃₄H₄₄F₄N₆O₁₂

[ Molecular Weight ]:
804.74

[ Appearance of Characters ]:
powder

[ Storage condition ]:
Store at -20° C

[ Water Solubility ]:
Water ：44 mg/mL (54.67 mM)

Related Compounds

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