524746-03-0

524746-03-0 structure

Name: Z-LEHD-FMK TFA
Chemical Name: Z-LEHD-FMK(Trifluoroacetate)
CAS Number: 524746-03-0
Molecular Formula: C₃₄H₄₄F₄N₆O₁₂
Molecular Weight: 804.74
Catalog: Signaling Pathways Apoptosis Caspase
Create Date: 2019-06-17 08:40:26
Modify Date: 2024-01-14 23:22:59
Z-LEHD-FMK TFA is an irreversible caspase-9 inhibitor, protects against lethal reperfusion injury and attenuate apoptosis[1][2].

Name	Z-LEHD-FMK(Trifluoroacetate)
Synonyms	MFCD01862609

Description	Z-LEHD-FMK TFA is an irreversible caspase-9 inhibitor, protects against lethal reperfusion injury and attenuate apoptosis[1][2].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Apoptosis >> Caspase Research Areas >> Inflammation/Immunology
Target	Caspase-9
References	[1]. M M Mocanu, et al. Caspase inhibition and limitation of myocardial infarct size: protection against lethal reperfusion injury. Br J Pharmacol. 2000 May;130(2):197-200. [2]. Graham Mouw, et al. Caspase-9 inhibition after focal cerebral ischemia improves outcome following reversible focal ischemia. Metab Brain Dis. 2002 Sep;17(3):143-51.