5-Hydroxymethyl xylouridine

Names

[ CAS No. ]:
52448-09-6

[ Name ]:
5-Hydroxymethyl xylouridine

Biological Activity

[Description]:

5-Hydroxymethyl xylouridine is a thymidine analog. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

[2]. Cavanagh BL, et al. Thymidine analogues for tracking DNA synthesis. Molecules. 2011 Sep 15;16(9):7980-93.  

Chemical & Physical Properties

[ Molecular Formula ]:
C10H14N2O7

[ Molecular Weight ]:
274.23

Related Compounds

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