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Emofolin sodium

Names

[ CAS No. ]:
52386-42-2

[ Name ]:
Emofolin sodium

Biological Activity

[Description]:

Ketotrexate sodium is an orally active antifolate and immunosuppressant. Ketotrexate sodium has good anti-inflammatory activity and is widely used in rheumatoid arthritis (RA). Ketotrexate sodium is used in research into cancer and autoimmune diseases[1][2].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Cell Cycle/DNA Damage >> Antifolate
Research Areas >> Inflammation/Immunology

[References]

[1]. Puig L. Methotrexate: new therapeutic approaches. Actas Dermosifiliogr. 2014 Jul-Aug;105(6):583-9.  

[2]. Torres RP, et al. Methotrexate: Implications of pharmacogenetics in the treatment of patients with Rheumatoid Arthritis. ARP Rheumatol. 2022 Oct 1;1(3):225-229.  

Chemical & Physical Properties

[ Density]:
1.58g/cm3

[ Molecular Formula ]:
C21H27N7O6

[ Molecular Weight ]:
473.48200

[ Exact Mass ]:
473.20200

[ PSA ]:
203.03000

[ LogP ]:
1.79280

Related Compounds