3-Bromo-2-chloropyridine
Names
[ CAS No. ]:
52200-48-3
[ Name ]:
3-Bromo-2-chloropyridine
[Synonym ]:
3-Bromo-2-chloropyridine
3-brom-2-chlorpyridin
MFCD00234007
Pyridine, 3-bromo-2-chloro-
bromo-3 chloro-2 pyridine
2-chloro-bromopyridine
3-bromo-2-chloro-pyridine
2-Chloro-3-bromopyridine
Biological Activity
[Description]:
[Related Catalog]:
Chemical & Physical Properties
[ Density]:
1.7±0.1 g/cm3
[ Boiling Point ]:
219.8±20.0 °C at 760 mmHg
[ Melting Point ]:
54-57 °C(lit.)
[ Molecular Formula ]:
C5H3BrClN
[ Molecular Weight ]:
192.44
[ Flash Point ]:
86.8±21.8 °C
[ Exact Mass ]:
190.913727
[ PSA ]:
12.89000
[ LogP ]:
2.33
[ Vapour Pressure ]:
0.2±0.4 mmHg at 25°C
[ Index of Refraction ]:
1.581
MSDS
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xi:Irritant;
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
S26-S36-S37/39
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ HS Code ]:
2933399090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2933399090
[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
Articles
J. Org. Chem. 68(26) , 10178-80, (2003)
Regioselective and univocal Suzuki cross-coupling reactions performed on halopyridinyl boronic acids provide a flexible and versatile route to a multigram scale synthesis of 2,2'-dichloro-3,4'-bipyrid...
Synthesis and antimicrobial activity studies of ortho-chlorodiarylamines and heteroaromatic tetracyclic systems in the benzo[b]thiophene series.Bioorg. Med. Chem. 14(20) , 6827-31, (2006)
ortho-Chlorodiarylamines in the 2,3,7-trimethylbenzo[b]thiophene series were prepared in high yields (70-85%) by C-N palladium-catalyzed cross-coupling using P(t-Bu)(3) as ligand and NaOt-Bu as base. ...
Synthesis of novel halopyridinylboronic acids and esters. Part 2: 2, 4, or 5-Halopyridin-3-yl-boronic acids and esters. Bouillon A, et al.Tetrahedron 58(17) , 3323-3328, (2002)