Isomaculosidine

Names

[ CAS No. ]:
518-96-7

[ Name ]:
Isomaculosidine

[Synonym ]:
Isomaculosidine
Furo[2,3-b]quinolin-4(9H)-one, 6,8-dimethoxy-9-methyl-
6,8-Dimethoxy-9-methylfuro[2,3-b]quinolin-4(9H)-one
Furo(2,3-b)quinolin-4(9H)-one, 6,8-dimethoxy-9-methyl-

Biological Activity

[Description]:

Isomaculosidine is an alkaloid that can be isolated from D. dasycarpus. Isomaculosidine can inhibit nitric oxide (NO) production in lipopolysaccharide (LPS)-stimulated BV2 microglial cells[1].

[Related Catalog]:

Signaling Pathways >> Immunology/Inflammation >> NO Synthase

Research Areas >> Neurological Disease

[References]

[1]. Jeong Seon Yoon, et al. Inhibitory alkaloids from Dictamnus dasycarpus root barks on lipopolysaccharide-induced nitric oxide production in BV2 cells. J Enzyme Inhib Med Chem. 2012 Aug;27(4):490-4.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
434.3±45.0 °C at 760 mmHg

[ Melting Point ]:
168-170℃

[ Molecular Formula ]:
C₁₄H₁₃NO₄

[ Molecular Weight ]:
259.257

[ Flash Point ]:
216.4±28.7 °C

[ Exact Mass ]:
259.084473

[ PSA ]:
53.60000

[ LogP ]:
1.70

[ Vapour Pressure ]:
0.0±1.0 mmHg at 25°C

[ Index of Refraction ]:
1.578

Safety Information

[ Hazard Codes ]:
Xi

[ HS Code ]:
2934999090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

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