o-Phenanthroline monohydrate

Names

[ Name ]:
o-Phenanthroline monohydrate

[Synonym ]:
1,10-Phenanthroline hydrate (1:1)
1,10-PHENANTHROLINE H2O
1,10-Phenanthroline hydrate
1,10-phehanthroline monohydrate
EINECS 200-629-2
1,10-phenanthroline monohydrate
4,5-Phenanthrolinemonohydrate
O-PHENANTHROLINE MONOHYDRATE
ORTHO-PHENANTHROLINE
1,10-phenanthroline-hydrate
MFCD00149973
1,10'-phenahthroline monohydrate
1,10-Phenanthroline, hydrate (1:1)
1,10-PHENANTHROLINE AR
O-PHENANTHROLINE HYDRATE
1,10-phenanthrolinemonorate
1,10-PHENANTHROLINE AR (H2O)

Biological Activity

[Description]:

o-Phenanthroline monohydrate (1,10-Phenanthroline monohydrate), a metal chelator, prevents the induction of chromosomal aberrations in streptozotocin-treated cells. o-Phenanthroline monohydrate forms a red chelate with Fe2+ that absorbs maximally at 510 nm[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Guan NanMu, et al. Synergistic inhibition between o-phenanthroline and chloride ion on cold rolled steel corrosion in phosphoric acid. Materials Chemistry and Physics Volume 86, Issue 1, 15 July 2004, Pages 59-68.

Chemical & Physical Properties

[ Density]:
1.10

[ Boiling Point ]:
365.1ºC at 760 mmHg

[ Melting Point ]:
100-104 °C(lit.)

[ Molecular Formula ]:
C₁₂H₁₀N₂O

[ Molecular Weight ]:
198.221

[ Flash Point ]:
164.8ºC

[ Exact Mass ]:
198.079315

[ PSA ]:
35.01000

[ LogP ]:
2.71870

[ Storage condition ]:
Store at RT.

[ Stability ]:
Stable. Incompatible with iron, other heavy metals, strong oxidizing agents, strong acids.

[ Water Solubility ]:
<0.01 g/100 mL at 21 ºC

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: SF8437000

CHEMICAL NAME :: 1,10-Phenanthroline, monohydrate

CAS REGISTRY NUMBER :: 5144-89-8

LAST UPDATED :: 199504

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C12-H8-N2.H2-O

MOLECULAR WEIGHT :: 198.24

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: DNA inhibition

TEST SYSTEM :: Rodent - mouse Ascites tumor

DOSE/DURATION :: 5 umol/L

REFERENCE :: CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 40,4092,1980 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X7001 No. of Facilities: 63 (estimated) No. of Industries: 6 No. of Occupations: 4 No. of Employees: 364 (estimated) No. of Female Employees: 27 (estimated)

Safety Information

[ Symbol ]:

GHS06, GHS09

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H301-H410

[ Precautionary Statements ]:
P273-P301 + P310-P501

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges

[ Hazard Codes ]:
T:Toxic

[ Risk Phrases ]:
R25;R50/53

[ Safety Phrases ]:
S45-S60-S61

[ RIDADR ]:
UN 2811 6.1/PG 3

[ WGK Germany ]:
3

[ RTECS ]:
SF8437000

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1

[ HS Code ]:
29339990

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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Related Compounds

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