1-Adamantyl bromomethyl ketone

[ Density]:
1.439g/cm3

[ Boiling Point ]:
320.3ºC at 760 mmHg

[ Melting Point ]:
76-79 °C(lit.)

[ Molecular Formula ]:
C₁₂H₁₇BrO

[ Molecular Weight ]:
257.16700

[ Flash Point ]:
61.1ºC

[ Exact Mass ]:
256.04600

[ PSA ]:
17.07000

[ LogP ]:
3.16680

[ Index of Refraction ]:
1.575

Click to get detail MSDS

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2914700090

Click to get detail synthetic route

[ HS Code ]: 2914700090

[ Summary ]:
HS: 2914700090 halogenated, sulphonated, nitrated or nitrosated derivatives of ketones and quinones, whether or not with other oxygen function Tax rebate rate:9.0% Supervision conditions:none VAT:17.0% MFN tariff:5.5% General tariff:30.0%

Discovery of adamantyl heterocyclic ketones as potent 11β-hydroxysteroid dehydrogenase type 1 inhibitors.

ChemMedChem 6 , 1439-51, (2011)

11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) plays a key role in converting intracellular cortisone to physiologically active cortisol, which is implicated in the development of several phenotyp...

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