1-Adamantyl bromomethyl ketone
Names
[ CAS No. ]:
5122-82-7
[ Name ]:
1-Adamantyl bromomethyl ketone
[Synonym ]:
1-(Adamantan-1-yl)-2-bromoethanone
1-(1-adamantyl)-2-bromoethanone
MFCD00074740
EINECS 225-860-6
Chemical & Physical Properties
[ Density]:
1.439g/cm3
[ Boiling Point ]:
320.3ºC at 760 mmHg
[ Melting Point ]:
76-79 °C(lit.)
[ Molecular Formula ]:
C12H17BrO
[ Molecular Weight ]:
257.16700
[ Flash Point ]:
61.1ºC
[ Exact Mass ]:
256.04600
[ PSA ]:
17.07000
[ LogP ]:
3.16680
[ Index of Refraction ]:
1.575
MSDS
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xi
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
S26-S37/39
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ HS Code ]:
2914700090
Synthetic Route
Customs
[ HS Code ]: 2914700090
[ Summary ]:
HS: 2914700090 halogenated, sulphonated, nitrated or nitrosated derivatives of ketones and quinones, whether or not with other oxygen function Tax rebate rate:9.0% Supervision conditions:none VAT:17.0% MFN tariff:5.5% General tariff:30.0%
Articles
ChemMedChem 6 , 1439-51, (2011)
11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) plays a key role in converting intracellular cortisone to physiologically active cortisol, which is implicated in the development of several phenotyp...