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α-Lipomycin

Names

[ CAS No. ]:
51053-40-8

[ Name ]:
α-Lipomycin

[Synonym ]:
3-[(4E)-4-{(2E,4E,6E,8E,10E)-13-[(2,6-Dideoxy-β-D-ribo-hexopyranosyl)oxy]-1-hydroxy-10,12,14-trimethyl-2,4,6,8,10-pentadecapentaen-1-ylidene}-1-methyl-3,5-dioxo-2-pyrrolidinyl]propanoic acid
2-Pyrrolidinepropanoic acid, 4-[(2E,4E,6E,8E,10E)-13-[(2,6-dideoxy-β-D-ribo-hexopyranosyl)oxy]-1-hydroxy-10,12,14-trimethyl-2,4,6,8,10-pentadecapentaen-1-ylidene]-1-methyl-3,5-dioxo-, (4E)-

Biological Activity

[Description]:

α-Lipomycin is an acyclic polyene antibiotic isolated from the gram-positive bacterium Streptomyces aureofaciens Tü117[1].

[Related Catalog]:

Research Areas >> Infection
Signaling Pathways >> Anti-infection >> Bacterial

[References]

[1]. Bihlmaier C, et al. Biosynthetic gene cluster for the polyenoyltetramic acid alpha-lipomycin. Antimicrob Agents Chemother. 2006;50(6):2113-2121.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
819.9±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C32H45NO9

[ Molecular Weight ]:
587.70

[ Flash Point ]:
449.7±34.3 °C

[ Exact Mass ]:
587.309448

[ LogP ]:
2.36

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.581

Related Compounds