Mitraphylline

Names

[ CAS No. ]:
509-80-8

[ Name ]:
Mitraphylline

[Synonym ]:
ajmalicine oxindole-B
HMS2267P09
Mitraphilline
EINECS 208-106-0
rubradinine
Mitraphylline
Mitraphyllin

Biological Activity

[Description]:

Mitraphylline is the major pentacyclic oxindolic alkaloid presented in Uncaria tomentosa. Mitraphylline inhibits lipopolysaccharide-mediated activation of primary human neutrophils[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Inflammation/Immunology

[References]

[1]. Montserrat-de la Paz S, et al. Mitraphylline inhibits lipopolysaccharide-mediated activation of primary human neutrophils. Phytomedicine. 2016 Feb 15;23(2):141-8.

Chemical & Physical Properties

[ Density]:
1.33 g/cm3

[ Boiling Point ]:
555.2ºC

[ Melting Point ]:
258-267 °C

[ Molecular Formula ]:
C₂₁H₂₄N₂O₄

[ Molecular Weight ]:
368.42600

[ Flash Point ]:
289.6ºC

[ Exact Mass ]:
368.17400

[ PSA ]:
67.87000

[ LogP ]:
2.13840

[ Index of Refraction ]:
1.635

Related Compounds

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