Arachidic acid

Names

[ CAS No. ]:
506-30-9

[ Name ]:
Arachidic acid

[Synonym ]:
Eicosanoic acid
Arachidic acid
Icosanoic acid
N-EICOSANOIC ACID
Arachic acid
MFCD00002755
EINECS 208-031-3

Biological Activity

[Description]:

Arachidonic acid (Icosanoic acid), a long-chain fatty acid, is present in all mammalian cells, typically esterified to membrane phospholipids, and is one of the most abundant polyunsaturated fatty acids present in human tissue[1][2].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Koppová I, et al. Analysis of fatty acid composition of anaerobic rumen fungi. Folia Microbiol (Praha). 2008;53(3):217-20.

[2]. Martin SA, et al. The discovery and early structural studies of arachidonic acid. J Lipid Res. 2016 Jul;57(7):1126-32.

Chemical & Physical Properties

[ Density]:
0.9±0.1 g/cm3

[ Boiling Point ]:
376.4±5.0 °C at 760 mmHg

[ Melting Point ]:
74-76 °C(lit.)

[ Molecular Formula ]:
C₂₀H₄₀O₂

[ Molecular Weight ]:
312.530

[ Flash Point ]:
169.7±12.5 °C

[ Exact Mass ]:
312.302826

[ PSA ]:
37.30000

[ LogP ]:
9.28

[ Vapour Pressure ]:
0.0±0.9 mmHg at 25°C

[ Index of Refraction ]:
1.457

[ Storage condition ]:
−20°C

[ Water Solubility ]:
practically insoluble

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: JX3780000

CHEMICAL NAME :: Eicosanoic acid

CAS REGISTRY NUMBER :: 506-30-9

LAST UPDATED :: 199709

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C20-H40-O2

MOLECULAR WEIGHT :: 312.60

WISWESSER LINE NOTATION :: QV19

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Implant

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1000 mg/kg

TOXIC EFFECTS :: Tumorigenic - neoplastic by RTECS criteria Kidney, Ureter, Bladder - tumors

REFERENCE :: CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 26,105,1966 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M2641 No. of Facilities: 858 (estimated) No. of Industries: 13 No. of Occupations: 24 No. of Employees: 12080 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M2641 No. of Facilities: 138 (estimated) No. of Industries: 5 No. of Occupations: 6 No. of Employees: 3362 (estimated) No. of Female Employees: 1859 (estimated)

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi: Irritant;Xn: Harmful;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
-

[ RTECS ]:
JX3780000

[ HS Code ]:
2915900090

Synthetic Route

Click to get detail synthetic route

Customs

[ HS Code ]: 2915900090

[ Summary ]:
2915900090 other saturated acyclic monocarboxylic acids and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:5.5% General tariff:30.0%

Articles

Direct detection of free fatty acids in edible oils using supercritical fluid chromatography coupled with mass spectrometry.

Food Chem. 170 , 463-9, (2014)

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Clin. Chim. Acta 438 , 126-34, (2014)

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Lipidomic analyses of female mice lacking hepatic lipase and endothelial lipase indicate selective modulation of plasma lipid species.

Lipids 49(6) , 505-15, (2014)

Hepatic lipase (HL) and endothelial lipase (EL) share overlapping and complementary roles in lipoprotein metabolism. The deletion of HL and EL alleles in mice raises plasma total cholesterol and phosp...