6-(Methylthio)purine

Names

[ CAS No. ]:
50-66-8

[ Name ]:
6-(Methylthio)purine

[Synonym ]:
6-methylsulfanyl-7H-purine
4-(METHYLTHIO)-1H-PYRAZOLO(3,4-D)PYRIMIDINE
6-(Methylthio)purine
EINECS 200-057-3
6-Methylmercaptopurine
MFCD00005576

Biological Activity

[Description]:

6-(Methylthio)purine (6-Methylmercaptopurine) is a small molecule that can be used for compound synthesis[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Sugimura H, Takei H. Synthesis of 6-alkylpurine derivatives by nickel-complex-catalyzed coupling reaction of 6-(methylthio) purine derivatives with Grignard reagents. Bulletin of the Chemical Society of Japan, 1985, 58(2): 664-666.

Chemical & Physical Properties

[ Density]:
1.47 g/cm3

[ Boiling Point ]:
470.2ºC at 760 mmHg

[ Melting Point ]:
219-223 °C

[ Molecular Formula ]:
C₆H₆N₄S

[ Molecular Weight ]:
166.20400

[ Exact Mass ]:
166.03100

[ PSA ]:
79.76000

[ LogP ]:
1.07480

[ Index of Refraction ]:
1.806

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UO8976000

CHEMICAL NAME :: Purine, 6-(methylthio)-

CAS REGISTRY NUMBER :: 50-66-8

LAST UPDATED :: 199709

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C6-H6-N4-S

MOLECULAR WEIGHT :: 166.22

WISWESSER LINE NOTATION :: T56 BM DN FN HNJ IS1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Parenteral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 115 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961- Volume(issue)/page/year: 71,618,1982

TYPE OF TEST :: LD10 - Lethal Dose

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 94 mg/kg

TOXIC EFFECTS :: Gastrointestinal - other changes

REFERENCE :: PMDCAY Progress in Medical Chemistry. (Elsevier Science Pub. Co., Inc., 52 Vanderbilt Ave., New York, NY 10017) V.1- 1961- Volume(issue)/page/year: 7,69,1970

Safety Information

[ Hazard Codes ]:
Xi

[ Safety Phrases ]:
S24/25

[ RTECS ]:
UO8976000

[ HS Code ]:
2933990090

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

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