N,N'-Dicyclohexyl-4-morpholinecarboxamidine
Names
[ CAS No. ]:
4975-73-9
[ Name ]:
N,N'-Dicyclohexyl-4-morpholinecarboxamidine
[Synonym ]:
4-Morpholinecarboximidamide, N,N'-dicyclohexyl-
N,N'-Dicyclohexyl-4-morpholine carboxamidine
4-(N,N'-Dicyclohexylcarbamimidoyl)morpholine
N,N'-Dicyclohexyl-4-morpholinecarboxamidine
4-(N,N'-Dicyclohexylamidino)morpholine
N,N-Dicyclohexyl-4-Morpholinecarboxamidine
MFCD00063252
N,N'-Dicyclohexyl-4-morpholinecarboximidamide
N,N'-Dicyclohexylmorpholine-4-carboximidamide
EINECS 225-622-1
N,N′-Dicyclohexyl-4-morpholinecarboxamidine
Chemical & Physical Properties
[ Density]:
1.2±0.1 g/cm3
[ Boiling Point ]:
423.2±55.0 °C at 760 mmHg
[ Melting Point ]:
105-107 °C(lit.)
[ Molecular Formula ]:
C17H31N3O
[ Molecular Weight ]:
293.448
[ Flash Point ]:
209.7±31.5 °C
[ Exact Mass ]:
293.246704
[ PSA ]:
36.86000
[ LogP ]:
2.99
[ Vapour Pressure ]:
0.0±1.0 mmHg at 25°C
[ Index of Refraction ]:
1.600
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- LQ4566500
- CHEMICAL NAME :
- Formamidine, N,N'-dicyclohexyl-1-morpholino-
- CAS REGISTRY NUMBER :
- 4975-73-9
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C17-H31-N3-O
- MOLECULAR WEIGHT :
- 293.51
- WISWESSER LINE NOTATION :
- T6N DOTJ AYUN- AL6TJ&M- AL6TJ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 20 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#07096
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ Hazard Codes ]:
Xi
[ Risk Phrases ]:
36/37/38
[ Safety Phrases ]:
26
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
LQ4566500
[ HS Code ]:
2934999090
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2934999090
[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
Articles
Antimicrob. Agents Chemother. 46(4) , 991-5, (2002)
The nucleotide phosphonates cidofovir (CDV) and cyclic cidofovir (cCDV) are potent antiviral compounds when administered parenterally but are not well absorbed orally. These compounds have been report...
Synthesis and diuretic activity of alkyl- and arylguanidine analogs of N,N'-dicyclohexyl-4-morpholinecarboxamidine in rats and dogs.J. Med. Chem. 37(22) , 3693-700, (1994)
Random screening identified N,N'-dicyclohexyl-4-morpholinecarboxamidine (U-18177, 1) as an orally effective nonkaliuretic diuretic in rats. The diuretic profile of 1 and its 1-adamantyl analog (U-3788...
An ATP-sensitive potassium channel blocker suppresses sodium-induced hypertension through increased secretion of urinary kallikrein.Hypertens. Res. 32(3) , 220-6, (2009)
It is suggested that an ATP-sensitive potassium channel blocker suppresses sodium-induced hypertension through increased secretion of urinary kallikrein. We reported that glibenclamide, an ATP-sensiti...