hypaphorine

Names

[ CAS No. ]:
487-58-1

[ Name ]:
hypaphorine

[Synonym ]:
(+)-Hypaphorine
Tryptophan, trimethylbetaine
(2S)-3-(1H-Indol-3-yl)-2-(trimethylammonio)propanoate
(S)-a-Carboxy-N,N,N-trimethyl-1H-indole-3-ethanaminium Inner Salt
1H-Indole-3-ethanaminium, α-carboxy-N,N,N-trimethyl-, inner salt, (αS)-
hypaphorine
tryptophan betaine
hypaphorin
1-Trimethylammonio-3-(3-indolyl)propionate
L-Hypaphorine
Glyyunnanenine

Biological Activity

[Description]:

Hypaphorine is an indole alkaloid isolated from Pisolithus tinctorius, and with neurological and glucose-lowering effects in rodents[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Metabolic Disease

Research Areas >> Neurological Disease

[References]

[1]. Ditengou FA, et al. Root hair elongation is inhibited by hypaphorine, the indole alkaloid from the ectomycorrhizal fungus Pisolithus tinctorius, and restored by indole-3-acetic acid. Planta. 2000 Oct;211(5):722-8.

[2]. Keller BO, et al. Hypaphorine is present in human milk in association with consumption of legumes. J Agric Food Chem. 2013 Aug 7;61(31):7654-60.

Chemical & Physical Properties

[ Melting Point ]:
255℃

[ Molecular Formula ]:
C₁₄H₁₈N₂O₂

[ Molecular Weight ]:
246.305

[ Exact Mass ]:
246.136826

[ PSA ]:
55.92000

[ LogP ]:
-2.12

[ Storage condition ]:
2-8℃

Safety Information

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
22-50

Related Compounds

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