<Suppliers Price>

Aminohexylgeldanamycin

Names

[ CAS No. ]:
485395-71-9

[ Name ]:
Aminohexylgeldanamycin

Biological Activity

[Description]:

Aminohexylgeldanamycin (AHGDM), a Geldanamycin derivative, is a potent HSP90 inhibitor. Aminohexylgeldanamycin shows antiangiogenic and antitumor activities[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Metabolic Enzyme/Protease >> HSP
Signaling Pathways >> Antibody-drug Conjugate >> ADC Cytotoxin
Signaling Pathways >> Cell Cycle/DNA Damage >> HSP

[Target]

HSP90


[References]

[1]. Greish K, et al. Anticancer and antiangiogenic activity of HPMA copolymer-aminohexylgeldanamycin-RGDfK conjugates for prostate cancer therapy. J Control Release. 2011;151(3):263-270.

Chemical & Physical Properties

[ Molecular Formula ]:
C34H52N4O8

[ Molecular Weight ]:
644.80

Related Compounds