4-Quinolinecarboxylicacid, 3-hydroxy-2-phenyl-
Names
[ CAS No. ]:
485-89-2
[ Name ]:
4-Quinolinecarboxylicacid, 3-hydroxy-2-phenyl-
[Synonym ]:
Hydroxycinchophene
3-hydroxy-2-phenyl-4-quinoline carboxylic acid
Reumartril
3-hydroxy-2-phenylquinoline-4-carboxylic cid
Oxinofen
Sintofene
Magnophenyl
2-Phenyl-3-hydroxy-chinchoninsaeure
oxicinchophen
3-hydroxy-2-phenyl-quinoline-4-carboxylic acid
Oxycinchophen
3-Hydroxy-2-phenylchinchoninsaeure
Chinoxone
Fenidrone
Magnofenyl
Chemical & Physical Properties
[ Density]:
1.374g/cm3
[ Boiling Point ]:
457.7ºC at 760mmHg
[ Melting Point ]:
206.5°C (rough estimate)
[ Molecular Formula ]:
C16H11NO3
[ Molecular Weight ]:
265.26300
[ Flash Point ]:
230.6ºC
[ Exact Mass ]:
265.07400
[ PSA ]:
70.42000
[ LogP ]:
3.30560
[ Vapour Pressure ]:
3.58E-09mmHg at 25°C
[ Index of Refraction ]:
1.712
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- GD3900000
- CHEMICAL NAME :
- Cinchoninic acid, 3-hydroxy-2-phenyl-
- CAS REGISTRY NUMBER :
- 485-89-2
- BEILSTEIN REFERENCE NO. :
- 0224526
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C16-H11-N-O3
- MOLECULAR WEIGHT :
- 265.28
- WISWESSER LINE NOTATION :
- T66 BNJ CR& DQ EVQ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 495 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 103,79,1951
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 400 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JHHBAI Bulletin of the Johns Hopkins Hospital. (Baltimore, MD) V.1-119, 1889-1966. For publisher information, see JHMJAX. Volume(issue)/page/year: 86,89,1950
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 144 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 103,79,1951
Safety Information
[ HS Code ]:
2933499090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2933499090
[ Summary ]:
2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%