pongamol

Names

[ CAS No. ]:
484-33-3

[ Name ]:
pongamol

[Synonym ]:
1-(4-METHOXY-5-BENZOFURANYL)-3-PHENYL-1,3-PROPANEDIONE
1-(4-methoxy-benzofuran-5-yl)-3-phenyl-propane-1,3-dione
1-(4-Methoxy-benzofuran-5-yl)-3-phenyl-propan-1,3-dion
pongamiaextract,pongamol
1-(4-Methoxybenzofuran-5-yl)-3-phenyl-1,3-propanedione
pongamolfrompongamiaglabrafruits

Biological Activity

[Description]:

Pongamol (Lanceolatin C) is potent α-glucosidase inhibitor (IC50=103.5 μM) and has free-radical (DPPH) scavenging,antihyperglycemic, and antihyperglycemic activities[1].

[Related Catalog]:

Research Areas >> Inflammation/Immunology

Research Areas >> Metabolic Disease

[References]

[1]. R Ranga Rao, et al. New furanoflavanoids, intestinal alpha-glucosidase inhibitory and free-radical (DPPH) scavenging, activity from antihyperglycemic root extract of Derris indica (Lam.). Bioorg Med Chem. 2009 Jul 15;17(14):5170-5.

Chemical & Physical Properties

[ Density]:
1.236 g/cm3

[ Boiling Point ]:
448.7ºC at 760 mmHg

[ Melting Point ]:
126-130ºC

[ Molecular Formula ]:
C₁₈H₁₄O₄

[ Molecular Weight ]:
294.30

[ Flash Point ]:
218.7ºC

[ Exact Mass ]:
294.08900

[ PSA ]:
56.51000

[ LogP ]:
3.89710

[ Vapour Pressure ]:
3.02E-10mmHg at 25°C

[ Index of Refraction ]:
1.646

Safety Information

[ Hazard Codes ]:
C

[ Risk Phrases ]:
50/53

[ Safety Phrases ]:
S60

[ RIDADR ]:
UN 3077 9/PG 3

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds

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