Eugenitin

Names

[ CAS No. ]:
480-12-6

[ Name ]:
Eugenitin

[Synonym ]:
Eugenitin
Eugenetin
5-Hydroxy-7-methoxy-2,6-dimethyl-chromen-4-on
4H-1-Benzopyran-4-one,5-hydroxy-7-methoxy-2,6-dimethyl
5-hydroxy-7-methoxy-2,6-dimethylchromone
5-hydroxy-7-methoxy-2,6-dimethyl-chromen-4-one

Biological Activity

[Description]:

Eugenitin is a polyketide isolated from the fungus Mycoleptodiscus indicus that is related to the South American medicinal plant. Eugenitin inhibits Leishmania major with LD50=39.9 μM. Eugenitin has low cytotoxicity (IC50 >131 μM) against several human cancer cell lines[1].

[Related Catalog]:

Research Areas >> Infection

[Target]

LD50: 39.9 μM (Leishmania major)[1]

[References]

[1]. Andrioli W J, et al. Mycoleptones A–C and polyketides from the endophyte Mycoleptodiscus indicus[J]. Journal of Natural Products, 2014, 77(1): 70-78.

Chemical & Physical Properties

[ Density]:
1.267g/cm3

[ Boiling Point ]:
402.2ºC at 760 mmHg

[ Molecular Formula ]:
C₁₂H₁₂O₄

[ Molecular Weight ]:
220.22100

[ Flash Point ]:
158.8ºC

[ Exact Mass ]:
220.07400

[ PSA ]:
59.67000

[ LogP ]:
2.12400

[ Vapour Pressure ]:
4.8E-07mmHg at 25°C

[ Index of Refraction ]:
1.58

Eugenitin

Names

Biological Activity

Chemical & Physical Properties

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds