480-12-6
480-12-6 structure
- Name: Eugenitin
- Chemical Name: 5-hydroxy-7-methoxy-2,6-dimethylchromen-4-one
- CAS Number: 480-12-6
- Molecular Formula: C12H12O4
- Molecular Weight: 220.22100
- Catalog: Research Areas Infection
- Create Date: 2018-02-21 08:00:00
- Modify Date: 2024-01-02 17:36:57
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Eugenitin is a polyketide isolated from the fungus Mycoleptodiscus indicus that is related to the South American medicinal plant. Eugenitin inhibits Leishmania major with LD50=39.9 μM. Eugenitin has low cytotoxicity (IC50 >131 μM) against several human cancer cell lines[1].
| Name | 5-hydroxy-7-methoxy-2,6-dimethylchromen-4-one |
|---|---|
| Synonyms |
Eugenitin
Eugenetin 5-Hydroxy-7-methoxy-2,6-dimethyl-chromen-4-on 4H-1-Benzopyran-4-one,5-hydroxy-7-methoxy-2,6-dimethyl 5-hydroxy-7-methoxy-2,6-dimethylchromone 5-hydroxy-7-methoxy-2,6-dimethyl-chromen-4-one |
| Description | Eugenitin is a polyketide isolated from the fungus Mycoleptodiscus indicus that is related to the South American medicinal plant. Eugenitin inhibits Leishmania major with LD50=39.9 μM. Eugenitin has low cytotoxicity (IC50 >131 μM) against several human cancer cell lines[1]. |
|---|---|
| Related Catalog | |
| Target |
LD50: 39.9 μM (Leishmania major)[1] |
| References |
| Density | 1.267g/cm3 |
|---|---|
| Boiling Point | 402.2ºC at 760 mmHg |
| Molecular Formula | C12H12O4 |
| Molecular Weight | 220.22100 |
| Flash Point | 158.8ºC |
| Exact Mass | 220.07400 |
| PSA | 59.67000 |
| LogP | 2.12400 |
| Vapour Pressure | 4.8E-07mmHg at 25°C |
| Index of Refraction | 1.58 |
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| Literature: Mukerjee; Seshadri Proceedings - Indian Academy of Sciences, Section A, 1953 , # 38 p. 207,217 Full Text Show Details Whalley Journal of the American Chemical Society, 1952 , vol. 74, p. 5795 |
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| Literature: Schoenberg et al. Journal of the American Chemical Society, 1953 , vol. 75, p. 4992,4994 Journal of the American Chemical Society, 1955 , vol. 77, p. 6721 |
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| Literature: Schoenberg et al. Journal of the American Chemical Society, 1953 , vol. 75, p. 4992,4994 Journal of the American Chemical Society, 1955 , vol. 77, p. 6721 |
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| Literature: Schoenberg et al. Journal of the American Chemical Society, 1953 , vol. 75, p. 4992,4994 Journal of the American Chemical Society, 1955 , vol. 77, p. 6721 |
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| Literature: Mukerjee et al. Proceedings - Indian Academy of Sciences, Section A, 1953 , # 37 p. 127,142 |
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| Literature: Mukerjee et al. Proceedings - Indian Academy of Sciences, Section A, 1953 , # 37 p. 127,142 |
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Detail
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| Literature: Mukerjee; Seshadri Proceedings - Indian Academy of Sciences, Section A, 1953 , # 38 p. 207,217 |
