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m-PEG7-Ms

Names

[ CAS No. ]:
477775-57-8

[ Name ]:
m-PEG7-Ms

[Synonym ]:
20-methoxy-(methylsulfonyl)oxy-3,6,9,12,15,18-hexaoxaeicosane
polyethyleneglycol-350 monomethylether methanesulfonate
20-methoxy--(methylsulfonyl)oxy-3,6,9,12,15,18-hexaoxaeicosane
Methanesulfonic acid 2-{2-[2-(2-{2-[2-(2-methoxy-ethoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-ethoxy}-ethyl ester
2,5,8,11,14,17,20-heptaoxadocosan-22-yl methanesulfonate
mPEG7-OMs

Biological Activity

[Description]:

m-PEG7-Ms is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker

[Target]

Cleavable


[In Vitro]

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

[References]

[1]. Sanxing Sun, et al. Triazolotriazine derivatives as a2a receptor antagonists. WO2020002969A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C16H34O10S

[ Molecular Weight ]:
418.50000

[ Exact Mass ]:
418.18700

[ PSA ]:
116.36000

[ LogP ]:
0.78940

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds