m-PEG7-azide

Names

[ CAS No. ]:
208987-04-6

[ Name ]:
m-PEG7-azide

[Synonym ]:
azidoheptaethylene glycol methyl ether
2,5,8,11,14,17,20-Heptaoxadocosane,22-azido

Biological Activity

[Description]:

m-PEG7-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> PROTAC >> PROTAC Linker

[In Vitro]

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

[References]

[1]. Lepage ML, et al. Design, synthesis and photochemical properties of the first examples of iminosugar clustersbased on fluorescent cores. Beilstein J Org Chem. 2015 May 6;11:659-67.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₅H₃₁N₃O₇

[ Molecular Weight ]:
365.42300

[ Exact Mass ]:
365.21600

[ PSA ]:
114.36000

[ LogP ]:
0.49546

m-PEG7-azide

Names

Biological Activity

Chemical & Physical Properties

Synthetic Route

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Precursor & DownStream

Precursor

DownStream

Related Compounds