LAH5

Names

[ Name ]:
LAH5

Biological Activity

[Description]:

LAH5 is an amphipathic cell-penetrating peptide. LAH5 effectively delivers CRISPR-Cas9 components into the nuclei of target cells by forming nanocomplexes with both RNP and RNP/HDR cargo[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Kichler A, et al. Histidine-rich amphipathic peptide antibiotics promote efficient delivery of DNA into mammalian cells. Proc Natl Acad Sci U S A. 2003 Feb 18;100(4):1564-8.

[2]. Öktem M, et al. Amphipathic Cell-Penetrating Peptide-Aided Delivery of Cas9 RNP for In Vitro Gene Editing and Correction. Pharmaceutics. 2023 Oct 20;15(10):2500.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₃₂H₂₂₄N₄₀O₂₇

[ Molecular Weight ]:
2803.44

Related Compounds

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