Uridine,2'-chloro-2'-deoxy-

Names

[ Name ]:
Uridine,2'-chloro-2'-deoxy-

[Synonym ]:
2-CHLORO-2-DEOXYURIDINE
MFCD00057379
2'-Chlor-2'-deoxy-uridin
2'-chloro-dU
2'-Chlor-2'-desoxyuridin
2'-Chloro-2'-deoxy-uridin

Biological Activity

[Description]:

2′-Chloro-2′-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Chemical & Physical Properties

[ Density]:
1.67g/cm3

[ Molecular Formula ]:
C₉H₁₁ClN₂O₅

[ Molecular Weight ]:
262.65

[ Exact Mass ]:
262.03600

[ PSA ]:
104.55000

[ Index of Refraction ]:
1.643

[ Storage condition ]:
-20°C

Safety Information

[ Hazard Codes ]:
Xn

Precursor & DownStream

Precursor

DownStream

Related Compounds

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