Triclosan-methyl

Names

[ Name ]:
Triclosan-methyl

[Synonym ]:
Benzene, 4-chloro-1-(2,4-dichlorophenoxy)-2-methoxy-
Benzene, 2,4-dichloro-1-(4-chloro-2-methoxyphenoxy)-
2,4-Dichloro-1-(4-chloro-2-methoxyphenoxy)benzene

Biological Activity

[Description]:

Triclosan-methyl is a transformation product of triclosan. Triclosan is a bactericide in personal care products such as toothpaste, shampoos, and soaps. Triclosan is also a stabilizing agent in a multitude of detergents and cosmetics[1].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Bacterial

[References]

[1]. Xijuan Chen, et al. Biodegradation of triclosan and formation of methyl-triclosan in activated sludge under aerobic conditions. Chemosphere. 2011 Jul;84(4):452-6.

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
358.7±42.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₃H₉Cl₃O₂

[ Molecular Weight ]:
303.568

[ Flash Point ]:
128.5±28.0 °C

[ Exact Mass ]:
301.966827

[ PSA ]:
18.46000

[ LogP ]:
4.74

[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.589

[ Storage condition ]:
Refrigerator

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS09

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H410

[ Precautionary Statements ]:
P273-P501

[ Personal Protective Equipment ]:
Eyeshields;Gloves;half-mask respirator (US);multi-purpose combination respirator cartridge (US)

[ Hazard Codes ]:
N

[ Risk Phrases ]:
50/53

[ Safety Phrases ]:
60-61

[ RIDADR ]:
UN 3082 9/PG 3

[ HS Code ]:
2909309090

Synthetic Route

Click to get detail synthetic route

Customs

[ HS Code ]: 2909309090

[ Summary ]:
2909309090 other aromatic ethers and their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

Articles

In-cell clean-up pressurized liquid extraction and gas chromatography-tandem mass spectrometry determination of hydrophobic persistent and emerging organic pollutants in coastal sediments.

J. Chromatogr. A. 1429 , 107-18, (2016)

The main goal of this work was to develop, optimize and validate a multi-residue method for the simultaneous determination of 97 contaminants, including fragrances, UV filters, repellents, endocrine d...

Related Compounds

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