Bay 55-9837

Names

[ Name ]:
Bay 55-9837

[Synonym ]:
BAY-55-9837
His-ser-asp-ala-val-phe-thr-asp-asn-tyr-thr-arg-leu-arg-lys-gln-val-ala-ala-lys-lys-tyr-leu-gln-ser-ile-lys-asp-lys-arg-tyr-NH2

Biological Activity

[Description]:

Bay 55-9837 is a potent and highly selective agonist of VPAC2, with a Kd of 0.65 nM. Bay 55-9837 may be a useful therapy for the research of type 2 diabetes[1].

[Related Catalog]:

Research Areas >> Metabolic Disease

Signaling Pathways >> GPCR/G Protein >> Glucagon Receptor

[Target]

Kd: 0.65 nM (VPAC2)[1]

[References]

[1]. Tsutsumi M, et, al. A potent and highly selective VPAC2 agonist enhances glucose-induced insulin release and glucose disposal: a potential therapy for type 2 diabetes. Diabetes. 2002 May; 51(5): 1453-60.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₄₈H₂₃₉ClN₄₄O₄₂

[ Molecular Weight ]:
3742.25000

[ Exact Mass ]:
3740.04000

[ PSA ]:
1675.16000

[ LogP ]:
5.32170

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.