Acetyl-(N-Me-Leu17,N-Me-Phe19)-Amyloid β-Protein (16-20) amide trifluoroacetate salt

Names

[ CAS No. ]:
461640-33-5

[ Name ]:
Acetyl-(N-Me-Leu17,N-Me-Phe19)-Amyloid β-Protein (16-20) amide trifluoroacetate salt

[Synonym ]:
A|A16-20m
Ac-Lys-(Me)Leu-Val-(Me)Phe-Phe-NH2 trifluoroacetate salt

Chemical & Physical Properties

[ Molecular Formula ]:
C41H60F3N7O8

[ Molecular Weight ]:
835.95200

[ Exact Mass ]:
835.44600

[ PSA ]:
245.79000

[ LogP ]:
6.92070

MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Articles

Design and characterization of a membrane permeable N-methyl amino acid-containing peptide that inhibits Abeta1-40 fibrillogenesis.

J. Pept. Res. 60 , 37-55, (2002)

Alzheimer's disease, Huntington's disease and prion diseases are part of a growing list of diseases associated with formation of beta-sheet containing fibrils. In a previous publication, we demonstrat...

Probing the role of backbone hydrogen bonding in beta-amyloid fibrils with inhibitor peptides containing ester bonds at alternate positions.

Biochemistry 42 , 475-485, (2003)

Protein-protein interactions are frequently mediated by stable, intermolecular beta-sheets. A number of cytokines and the HIV Protease, for example, dimerize through beta-sheet motifs. Evidence also s...


More Articles


Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.