4-(Trifluoromethoxy)aniline

Names

[ CAS No. ]:
461-82-5

[ Name ]:
4-(Trifluoromethoxy)aniline

[Synonym ]:
4-aminophenyl trifluoromethyl ether
ZR DOXFFF
4-TRIFLUORO METHOXYLAMINE
4-(trifluoromethoxy)benzeneamine
4-Trifluoromethoxyaniline
EINECS 207-317-5
α,α,α-Trifluoro-p-anisidine
4-trifluoromethoxy-aniline
Riluzole Related Compound A
4-trifluoromethoxyaniune
4-(Trifluoromethoxy)benzenamine
4-(Trifluoromethoxy)aniline
Benzenamine, 4-(trifluoromethoxy)-
p-Trifluoromethoxyaniline
4-amino-trifluoromethoxybenzene
4-Trifluoroethoxyaniline
p-Aminophenyl trifluoromethyl ether
AMino TrifluoroMethoxybenzene
MFCD00041314

Biological Activity

[Description]:

4-(Trifluoromethoxy)aniline is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
192.4±0.0 °C at 760 mmHg

[ Molecular Formula ]:
C₇H₆F₃NO

[ Molecular Weight ]:
177.13

[ Flash Point ]:
80.6±0.0 °C

[ Exact Mass ]:
177.040146

[ PSA ]:
35.25000

[ LogP ]:
1.78

[ Vapour Pressure ]:
0.5±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.481

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS05, GHS06, GHS08

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H301-H310-H315-H318-H373

[ Precautionary Statements ]:
P280-P301 + P310-P302 + P350-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xn:Harmful

[ Risk Phrases ]:
R20/21/22;R36/37/38

[ Safety Phrases ]:
S26-S36/37/39-S45

[ RIDADR ]:
UN 2941 6.1/PG 3

[ WGK Germany ]:
2

[ Hazard Class ]:
6.1

[ HS Code ]:
2921420090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2922299090

[ Summary ]:
2922299090. other amino-naphthols and other amino-phenols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

The metabolism of 4-trifluoromethoxyaniline and [13C]-4-trifluoromethoxyacetanilide in the rat: detection and identification of metabolites excreted in the urine by NMR and HPLC-NMR.

J. Pharm. Biomed. Anal. 28(5) , 875-85, (2002)

A combination of 19F, 1H NMR and HPLC-NMR spectroscopic approaches have been used to quantify and identify the urinary-excreted metabolites of 4-trifluoromethoxyaniline (4-TFMeA) and its [13C]-labelle...

Synthesis of liquid-crystalline poly (meth) acrylates with 4-trifluoromethoxy-azobenzene mesogenic side-groups. Prescher D, et al.

J. Fluor. Chem. 74(2) , 185-89, (1995)

Microwave-assisted multistep synthesis of functionalized 4-arylquinolin-2 (1 H)-ones using palladium-catalyzed cross-coupling chemistry. Glasnov TN, et al.

J. Org. Chem. 70(10) , 3865-70, (2005)

Related Compounds

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