Dibenzyl L-glutamate hydrochloride

Names

[ Name ]:
Dibenzyl L-glutamate hydrochloride

[Synonym ]:
dibenzyl (2S)-2-aminopentanedioate,hydrochloride
Dibenzyl glutamate hydrochloride (1:1)
H-Glu(OBzl)-OBzl·HCl
Glutamic acid, bis(phenylmethyl) ester, hydrochloride (1:1)

Biological Activity

[Description]:

H-Glu(OBzl)-OBzl.HCl is a glutamic acid derivative[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].

[References]

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.

Chemical & Physical Properties

[ Boiling Point ]:
453.5ºC at 760 mmHg

[ Melting Point ]:
102.0 to 106.0 °C

[ Molecular Formula ]:
C₁₉H₂₂ClNO₄

[ Molecular Weight ]:
363.835

[ Flash Point ]:
165.6ºC

[ Exact Mass ]:
363.123749

[ PSA ]:
78.62000

[ LogP ]:
4.08300

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: MA0885000

CHEMICAL NAME :: L-Glutamic acid, bis(phenylmethyl) ester, hydrochloride

CAS REGISTRY NUMBER :: 4561-10-8

LAST UPDATED :: 199312

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C19-H21-N-O4.Cl-H

MOLECULAR WEIGHT :: 363.87

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 25,246,1991

Safety Information

[ Hazard Codes ]:
Xi

[ HS Code ]:
2922499990

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2922499990

[ Summary ]:
HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%