N6-Succinyl Adenosine

Names

[ Name ]:
N6-Succinyl Adenosine

[Synonym ]:
(2S)-2-[[9-[(2S,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-6-yl]amino]butanedioic acid
N6-Succinyl Adenosine

Biological Activity

[Description]:

Succinyladenosine, the metabolic product of dephosphorylation of intracellular adenylosuccinic acid (S-AMP) by cytosolic 5-nucleotidase, is a biochemical marker of adenylosuccinase (ASL) deficiency[1].

[Related Catalog]:

Research Areas >> Metabolic Disease

[Target]

Human Endogenous Metabolite

[In Vitro]

The presence of high concentrations of Succinyladenosine (S-Ado) in the human cerebrospinal fluid (CSF) in the range of 100–500 μmol/L is a diagnostic marker for inherited enzyme deficiency of ASL[1].

[References]

[1]. J Krijt, et al. Identification and Determination of Succinyladenosine in Human Cerebrospinal Fluid . J Chromatogr B Biomed Sci Appl. 1999 Apr 16;726(1-2):53-8.

Chemical & Physical Properties

[ Density]:
2.02g/cm3

[ Boiling Point ]:
816.4ºC at 760mmHg

[ Molecular Formula ]:
C₁₄H₁₇N₅O₈

[ Molecular Weight ]:
383.31300

[ Flash Point ]:
447.6ºC

[ Exact Mass ]:
383.10800

[ PSA ]:
200.15000

[ Storage condition ]:
-20°C

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds

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