2-Amino-4-(trifluoromethyl)phenol

Names

[ CAS No. ]:
454-81-9

[ Name ]:
2-Amino-4-(trifluoromethyl)phenol

[Synonym ]:
2-AMINO-4-(TRIFLUOROMETHYL)PHENOL HYDROCHLORIDE
3-amino-4-hydroxybenzotrifluoride
2-hydroxyaniline
5-trifluoromethyl-2-hydroxyaniline
2-hydroxy-5-(trifluoromethyl)aniline
2-Amino-4-(trifluoromethyl)phenol
2-amino-4-trifluoromethylphenol
Phenol, 2-amino-4-(trifluoromethyl)-

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
234.5±40.0 °C at 760 mmHg

[ Melting Point ]:
121-122°C

[ Molecular Formula ]:
C₇H₆F₃NO

[ Molecular Weight ]:
177.124

[ Flash Point ]:
95.6±27.3 °C

[ Exact Mass ]:
177.040146

[ PSA ]:
46.25000

[ LogP ]:
2.66

[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.516

[ Storage condition ]:
2-8°C

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: GO6840000

CHEMICAL NAME :: p-Cresol, 2-amino-alpha,alpha,alpha-trifluoro-

CAS REGISTRY NUMBER :: 454-81-9

BEILSTEIN REFERENCE NO. :: 2094573

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C7-H6-F3-N-O

MOLECULAR WEIGHT :: 177.14

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >1 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961- Volume(issue)/page/year: 57,1763,1968

Safety Information

[ Hazard Codes ]:
Xi

[ HS Code ]:
2922299090

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2922299090

[ Summary ]:
2922299090. other amino-naphthols and other amino-phenols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%