3-Nitro-4-chlorobenzotrifluoride
Names
[ CAS No. ]:
121-17-5
[ Name ]:
3-Nitro-4-chlorobenzotrifluoride
[Synonym ]:
4-chloro-3-nitro-benzotrifluorid
4-chloro-α,α,α-trifluoro-3-nitrotoluene
Benzene, 1-chloro-2-nitro-4-(trifluoromethyl)-
4-CHLORO-3-NITROTRIFLUOROBENZENE
MFCD00007084
4-chloro-3-nitro-trifluoroMethyl
3-Nitro-4-chlorobenzotrifluoride
Toluene, 4-chloro-α,α,α-trifluoro-3-nitro-
2-chloro-5-trifluoromethyl-nitrobenzene
CMNT
4-CHLORO-3-NITROBENZOTRIFLLUORIDE
4-chloro-3-nitro-1-trifluoromethyl-benzene
MNT-Cl
4-trifluoromethyl-2-nitro-1-chlorobenzene
4-Chloro-3-nitrobenzotrifluoride
Benzene, 1-chloro-2-nitro-4- (trifluoromethyl)-
3-nitro-4-chlorotrifluoromethylbenzene
4-chloro-1-trifluo
1-Chloro-2-nitro-4-(trifluoromethyl)benzene
EINECS 204-451-6
4-Chloro-3-nitro-4-(trifluoromethyl)benzene
Chemical & Physical Properties
[ Density]:
1.5±0.1 g/cm3
[ Boiling Point ]:
225.3±35.0 °C at 760 mmHg
[ Melting Point ]:
-2 °C
[ Molecular Formula ]:
C7H3ClF3NO2
[ Molecular Weight ]:
225.552
[ Flash Point ]:
101.7±0.0 °C
[ Exact Mass ]:
224.980438
[ PSA ]:
45.82000
[ LogP ]:
3.08
[ Vapour Pressure ]:
0.1±0.4 mmHg at 25°C
[ Index of Refraction ]:
1.493
[ Water Solubility ]:
Insoluble
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- XS9140000
- CHEMICAL NAME :
- Toluene, 4-chloro-3-nitro-alpha,alpha,alpha-trifluoro-
- CAS REGISTRY NUMBER :
- 121-17-5
- BEILSTEIN REFERENCE NO. :
- 0523986
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 7
- MOLECULAR FORMULA :
- C7-H3-Cl-F3-N-O2
- MOLECULAR WEIGHT :
- 225.56
- WISWESSER LINE NOTATION :
- WNR BG EXFFF
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1075 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - tremor Behavioral - ataxia
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 400 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - tremor Behavioral - ataxia
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 56 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 280 mg/kg/4W-I
- TOXIC EFFECTS :
- Brain and Coverings - changes in brain weight Liver - changes in liver weight Blood - changes in erythrocyte (RBC) count
MUTATION DATA
- TYPE OF TEST :
- Unscheduled DNA synthesis
- TEST SYSTEM :
- Human Embryo
- DOSE/DURATION :
- 1 gm/L
- REFERENCE :
- AISSAW Annali dell'Istituto Superiore di Sanita. (Istituto Poligrafico e Zecca dello Stato, Piazza Verdi, 10 Rome, Italy) V.1- 1965- Volume(issue)/page/year: 18,123,1982
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H302-H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ Hazard Codes ]:
Xn:Harmful
[ Risk Phrases ]:
R22;R36/37/38
[ Safety Phrases ]:
S26-S36-S37/39
[ RIDADR ]:
UN 2307 6.1/PG 2
[ WGK Germany ]:
2
[ RTECS ]:
XS9140000
[ Packaging Group ]:
II
[ Hazard Class ]:
6.1
[ HS Code ]:
29049085
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2904909090
[ Summary ]:
HS:2904909090 sulphonated, nitrated or nitrosated derivatives of hydrocarbons, whether or not halogenated VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%
Articles
Ital. Gen. Rev. Dermatol. 15(2) , 107-12, (1978)
A case of occupational contact dermatitis in a female chemical pharmaceutical laboratory researcher is described. The allergological investigation revealed a state of sensitization to three mono-nitro...
In vitro mutational studies with trifluralin and trifluorotoluene derivatives.Ann. Ist. Super. Sanita 18(1) , 123-6, (1982)
[Subchronic oral toxicity in the rat of 3-nitro-4-chloro-alpha,alpha,alpha-trifluorotoluene (NCTT)].
Ann. Ist. Super. Sanita 19(2-3) , 385-9, (1983)