SPP-DM1

Names

[ CAS No. ]:
452072-20-7

[ Name ]:
SPP-DM1

Biological Activity

[Description]:

SPP-DM1 is a drug-linker conjugate for ADC with potent antitumor activity by using DM1 (a potent microtubule-disrupting agent), linked via the ADC linker SPP[1].

[Related Catalog]:

Research Areas >> Cancer

[Target]

Maytansinoids

[References]

[1]. Manu Lopus et al. Maytansine and Cellular Metabolites of Antibody-Maytansinoid Conjugates Strongly Suppress Microtubule Dynamics by Binding to Microtubules.

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Molecular Formula ]:
C₄₄H₅₉ClN₄O₁₄S₂

[ Molecular Weight ]:
967.541

[ Exact Mass ]:
966.315796

[ LogP ]:
4.78

[ Index of Refraction ]:
1.617

Related Compounds

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