SPP

Names

[ Name ]:
SPP

[Synonym ]:
N-succinimidyl 4-(2-pyridyldithio)pentanoate
SPP
N-succinimidyl-4-(2-pyridyldithio) pentanoate
N-succinimidyl-4-(2-pyridyldithio)pentanoate
4-(Pyridin-2-yldisulfanyl)-pentanoic acid 2,5-dioxo-pyrrolidin-1-yl ester
N-succinimidyl 4-(pyridin-2-yldithio)-pentanoate

Biological Activity

[Description]:

SPP is a disulfide linker, can be used to form cytotoxic compound- linker conjugate[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker

[Target]

Alkyl/ether

[References]

[1]. Widdison W, et al. Metabolites of antibody-maytansinoid conjugates: characteristics and in vitro potencies. Mol Pharm. 2015 Jun 1;12(6):1762-73.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₄H₁₆N₂O₄S₂

[ Molecular Weight ]:
340.41800

[ Exact Mass ]:
340.05500

[ PSA ]:
127.17000

[ LogP ]:
2.53570

SPP

Names

Biological Activity

Chemical & Physical Properties

Related Compounds