Topoisomerase II inhibitor 15

Names

[ CAS No. ]:
451516-79-3

[ Name ]:
Topoisomerase II inhibitor 15

Biological Activity

[Description]:

Topoisomerase II inhibitor 15 (compound 2g) is a Topoisomerase II inhibitor. Topoisomerase II inhibitor 15 potently is an apoptotic inducer with greater selectivity against head and neck tumors[1].

[Related Catalog]:

Signaling Pathways >> Apoptosis >> Apoptosis
Research Areas >> Cancer
Signaling Pathways >> Cell Cycle/DNA Damage >> Topoisomerase

[References]

[1]. Ahmed A Al-Karmalawy, et al. Novel fused imidazotriazines acting as promising top. II inhibitors and apoptotic inducers with greater selectivity against head and neck tumors: Design, synthesis, and biological assessments. Eur J Med Chem. 2023 Nov 5;259:115661.  

Chemical & Physical Properties

[ Molecular Formula ]:
C15H11Cl2N5

[ Molecular Weight ]:
332.19


Related Compounds

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