2'-aminobenzanilide

Names

[ Name ]:
2'-aminobenzanilide

[Synonym ]:
Anthranilanilide
N-Phenylanthranilamide
N-phenyl-2-aminobenzamide
Benzamide,2-amino-N-phenyl
MFCD00034792
N1-phenyl-2-aminobenzamide
Benzanilide,2-amino
amino-benzanilide
2-Aminobenzanilide
EINECS 224-599-5
2-amino-N-phenyl-benzamide

Biological Activity

[Description]:

2-Aminobenzamide is a neutral and stable compound used as fluorescent tag, numerously in Glycan analysis. 2-aminobenzamide acts as the starting material for several important reactions like Bargellini reaction as an competent ambident nucleophile. Specifically 2-aminobenzamide and its derivatives are used in the blood coagulation cascade[1][2].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Pallavi More, et al. Natural surfactant mediated phytosynthesis and solvatochromic fluorescence of 2-aminobenzamide derivatives. RSC Adv., 2014,4, 63039-63047.

Chemical & Physical Properties

[ Density]:
1.244 g/cm3

[ Boiling Point ]:
309.6ºC at 760 mmHg

[ Melting Point ]:
133-134°C

[ Molecular Formula ]:
C₁₃H₁₂N₂O

[ Molecular Weight ]:
212.24700

[ Flash Point ]:
141ºC

[ Exact Mass ]:
212.09500

[ PSA ]:
55.12000

[ LogP ]:
3.17530

[ Index of Refraction ]:
1.688

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: CV2325000

CHEMICAL NAME :: Benzamide, 2-amino-N-phenyl-

CAS REGISTRY NUMBER :: 4424-17-3

BEILSTEIN REFERENCE NO. :: 0782786

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C13-H12-N2-O

MOLECULAR WEIGHT :: 212.27

WISWESSER LINE NOTATION :: ZR BVMR

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 14,963,1971

Safety Information

[ Safety Phrases ]:
S22-S24/25

[ RTECS ]:
CV2325000