JIP-1(153-163)

Names

[ Name ]:
JIP-1(153-163)

[Synonym ]:
L-Arginyl-L-prolyl-L-lysyl-L-arginyl-L-prolyl-L-threonyl-L-threonyl-L-leucyl-L-asparaginyl-L-leucyl-L-phenylalaninamide
L-Phenylalaninamide, L-arginyl-L-prolyl-L-lysyl-L-arginyl-L-prolyl-L-threonyl-L-threonyl-L-leucyl-L-asparaginyl-L-leucyl-

Biological Activity

[Description]:

JIP-1(153-163) (TI-JIP) is a peptide inhibitor of c-JNK, based on residues 153-163 of JNK-interacting protein-1 (JIP-1) (Modifications: Phe-11 = C-terminal amide)[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> MAPK/ERK Pathway >> JNK

[References]

[1]. Renae K Barr, et al. Identification of the critical features of a small peptide inhibitor of JNK activity. J Biol Chem. 2002 Mar 29;277(13):10987-97.

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Molecular Formula ]:
C₆₁H₁₀₄N₂₀O₁₄

[ Molecular Weight ]:
1341.604

[ Exact Mass ]:
1340.804077

[ LogP ]:
-2.48

[ Appearance of Characters ]:
White lyophilised solid

[ Index of Refraction ]:
1.660

[ Storage condition ]:
Desiccate at -20°C

[ Water Solubility ]:
Soluble to 1 mg/ml in H2O

Related Compounds

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