TKN1

Names

[ Name ]:
TKN1

[Synonym ]:
Benzamide, N-[2-hydroxy-5-(1-methylethyl)phenyl]-2-methoxy-
N-(2-Hydroxy-5-isopropylphenyl)-2-methoxybenzamide

Biological Activity

[Description]:

A small molecule allosteric inhibitor of TREK channels with IC50 of 6.5, 4.4 and 15.7 uM for TREK-1, TREK-2 and TRAAK, respectively.

[References]

References 1. Luo Q, et al. Nat Commun. 2017 Aug 29;8(1):378. View Related Products by Target Potassium Channel

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
361.7±42.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₇H₁₉NO₃

[ Molecular Weight ]:
285.338

[ Flash Point ]:
172.6±27.9 °C

[ Exact Mass ]:
285.136505

[ LogP ]:
3.69

[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.611

Related Compounds

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