432533-28-3
432533-28-3 structure
- Name: TKN1
- Chemical Name: N-(2-Hydroxy-5-isopropylphenyl)-2-methoxybenzamide
- CAS Number: 432533-28-3
- Molecular Formula: C17H19NO3
- Molecular Weight: 285.338
- Create Date: 2020-01-11 12:19:01
- Modify Date: 2024-01-22 18:09:38
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A small molecule allosteric inhibitor of TREK channels with IC50 of 6.5, 4.4 and 15.7 uM for TREK-1, TREK-2 and TRAAK, respectively.
| Name | N-(2-Hydroxy-5-isopropylphenyl)-2-methoxybenzamide |
|---|---|
| Synonyms |
Benzamide, N-[2-hydroxy-5-(1-methylethyl)phenyl]-2-methoxy-
N-(2-Hydroxy-5-isopropylphenyl)-2-methoxybenzamide |
| Description | A small molecule allosteric inhibitor of TREK channels with IC50 of 6.5, 4.4 and 15.7 uM for TREK-1, TREK-2 and TRAAK, respectively. |
|---|---|
| References | References 1. Luo Q, et al. Nat Commun. 2017 Aug 29;8(1):378. View Related Products by Target Potassium Channel |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 361.7±42.0 °C at 760 mmHg |
| Molecular Formula | C17H19NO3 |
| Molecular Weight | 285.338 |
| Flash Point | 172.6±27.9 °C |
| Exact Mass | 285.136505 |
| LogP | 3.69 |
| Vapour Pressure | 0.0±0.8 mmHg at 25°C |
| Index of Refraction | 1.611 |