2-Benzylthioadenosine

Names

[ CAS No. ]:
43157-48-8

[ Name ]:
2-Benzylthioadenosine

[Synonym ]:
Adenosine, 2-[(phenylmethyl)thio]-
2-(Benzylsulfanyl)adenosine

Biological Activity

[Description]:

2-Benzylthioadenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

[2]. Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500.  

Chemical & Physical Properties

[ Density]:
1.7±0.1 g/cm3

[ Boiling Point ]:
786.3±70.0 °C at 760 mmHg

[ Molecular Formula ]:
C17H19N5O4S

[ Molecular Weight ]:
389.43

[ Flash Point ]:
429.4±35.7 °C

[ Exact Mass ]:
389.115784

[ LogP ]:
1.48

[ Vapour Pressure ]:
0.0±2.9 mmHg at 25°C

[ Index of Refraction ]:
1.807

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.