7-chloro-5-(2-chlorophenyl)-3-hydroxy-1,3-dihydropyrido[3,2-e][1,4]diazepin-2-one

Names

[ Name ]:
7-chloro-5-(2-chlorophenyl)-3-hydroxy-1,3-dihydropyrido[3,2-e][1,4]diazepin-2-one

[Synonym ]:
Lopirazepam [INN]
2H-Pyrido(3,2-e)-1,4-diazepin-2-one,1,3-dihydro-7-chloro-5-(2-chlorophenyl)-3-hydroxy
3-Hydroxy-5-o-chlorophenyl-6-aza-7-chloro-1,2-dihydro-3H-1,4-benzodiazepinone
EINECS 255-974-1
Lopirazepamum [INN-Latin]
2H-Pyrido(3,2-e)-1,4-diazepin-2-one,7-chloro-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy
7-chloro-5-(2-chloro-phenyl)-3-hydroxy-1,3-dihydro-pyrido[3,2-e][1,4]diazepin-2-one
7-chloro-5-(2-chlorophenyl)-3-hydroxy-1,3-dihydro-2h-pyrido[3,2-e][1,4]diazepin-2-one
7-Chloro-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy-2H-pyrido(3,2-e)-1,4-diazepin-2-one
Lopirazepam

Biological Activity

[Description]:

Lopirazepam is a potent small molecule GABAA receptor agonist, which can be used to treat anxiety disorders, insomnia, epilepsy and other diseases.

[References]

1. Fabian A,et al. Veränderungen der Dauer der Schlafzyklen unter Flurazepam und Lopirazepam [Changes in the length of sleep cycles during administration of flurazepam and lopirazepam]. EEG EMG Z Elektroenzephalogr Elektromyogr Verwandte Geb. 1984 Sep;15(3):151-8. German.

Chemical & Physical Properties

[ Density]:
1.61g/cm3

[ Boiling Point ]:
563.9ºC at 760mmHg

[ Molecular Formula ]:
C₁₄H₉Cl₂N₃O₂

[ Molecular Weight ]:
322.14600

[ Flash Point ]:
294.8ºC

[ Exact Mass ]:
321.00700

[ PSA ]:
78.07000

[ LogP ]:
2.01700

[ Index of Refraction ]:
1.726

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.