42863-81-0
42863-81-0 structure
- Name: 7-chloro-5-(2-chlorophenyl)-3-hydroxy-1,3-dihydropyrido[3,2-e][1,4]diazepin-2-one
- Chemical Name: 7-chloro-5-(2-chlorophenyl)-3-hydroxy-1,3-dihydropyrido[3,2-e][1,4]diazepin-2-one
- CAS Number: 42863-81-0
- Molecular Formula: C14H9Cl2N3O2
- Molecular Weight: 322.14600
- Create Date: 2018-07-07 12:58:32
- Modify Date: 2024-04-05 19:27:05
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Lopirazepam is a potent small molecule GABAA receptor agonist, which can be used to treat anxiety disorders, insomnia, epilepsy and other diseases.
| Name | 7-chloro-5-(2-chlorophenyl)-3-hydroxy-1,3-dihydropyrido[3,2-e][1,4]diazepin-2-one |
|---|---|
| Synonyms |
Lopirazepam [INN]
2H-Pyrido(3,2-e)-1,4-diazepin-2-one,1,3-dihydro-7-chloro-5-(2-chlorophenyl)-3-hydroxy 3-Hydroxy-5-o-chlorophenyl-6-aza-7-chloro-1,2-dihydro-3H-1,4-benzodiazepinone EINECS 255-974-1 Lopirazepamum [INN-Latin] 2H-Pyrido(3,2-e)-1,4-diazepin-2-one,7-chloro-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy 7-chloro-5-(2-chloro-phenyl)-3-hydroxy-1,3-dihydro-pyrido[3,2-e][1,4]diazepin-2-one 7-chloro-5-(2-chlorophenyl)-3-hydroxy-1,3-dihydro-2h-pyrido[3,2-e][1,4]diazepin-2-one 7-Chloro-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy-2H-pyrido(3,2-e)-1,4-diazepin-2-one Lopirazepam |
| Description | Lopirazepam is a potent small molecule GABAA receptor agonist, which can be used to treat anxiety disorders, insomnia, epilepsy and other diseases. |
|---|---|
| References | 1. Fabian A,et al. Veränderungen der Dauer der Schlafzyklen unter Flurazepam und Lopirazepam [Changes in the length of sleep cycles during administration of flurazepam and lopirazepam]. EEG EMG Z Elektroenzephalogr Elektromyogr Verwandte Geb. 1984 Sep;15(3):151-8. German. |
| Density | 1.61g/cm3 |
|---|---|
| Boiling Point | 563.9ºC at 760mmHg |
| Molecular Formula | C14H9Cl2N3O2 |
| Molecular Weight | 322.14600 |
| Flash Point | 294.8ºC |
| Exact Mass | 321.00700 |
| PSA | 78.07000 |
| LogP | 2.01700 |
| Index of Refraction | 1.726 |