Isobutylparaben
Names
[ CAS No. ]:
4247-02-3
[ Name ]:
Isobutylparaben
[Synonym ]:
Benzoic acid, 4-hydroxy-, 2-methylpropyl ester
EINECS 224-208-8
Isobutyl 4-hydroxybenzoate
Isobutyl paraben
Benzoic acid, 4-hydroxy-, 2-methylpropyl ester (9CI)
2-methylpropyl 4-hydroxybenzoate
MFCD00020167
Biological Activity
[Description]:
[Related Catalog]:
[References]
Chemical & Physical Properties
[ Density]:
1.1±0.1 g/cm3
[ Boiling Point ]:
302.3±15.0 °C at 760 mmHg
[ Melting Point ]:
76°C
[ Molecular Formula ]:
C11H14O3
[ Molecular Weight ]:
194.227
[ Flash Point ]:
125.4±13.2 °C
[ Exact Mass ]:
194.094299
[ PSA ]:
46.53000
[ LogP ]:
3.28
[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C
[ Index of Refraction ]:
1.524
[ Storage condition ]:
0-6°C
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- DH2247000
- CHEMICAL NAME :
- Benzoic acid, p-hydroxy-, isobutyl ester
- CAS REGISTRY NUMBER :
- 4247-02-3
- BEILSTEIN REFERENCE NO. :
- 2642305
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C11-H14-O3
- MOLECULAR WEIGHT :
- 194.25
- WISWESSER LINE NOTATION :
- QR DVO1Y1&1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 2600 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 128,135,1960
Safety Information
[ Symbol ]:
GHS07, GHS09
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H315-H319-H411
[ Precautionary Statements ]:
P305 + P351 + P338
[ Hazard Codes ]:
Xn: Harmful;
[ Risk Phrases ]:
51/53
[ Safety Phrases ]:
S22-S24/25
[ RIDADR ]:
UN 3077 9/PG 3
[ RTECS ]:
DH2247000
[ HS Code ]:
2918290000
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2918290000
[ Summary ]:
HS: 2918290000 other carboxylic acids with phenol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) VAT:17.0% MFN tariff:6.5% General tariff:30.0%
Articles
Anal. Bioanal. Chem 407(9) , 2509-18, (2015)
Phthalates, bisphenol A (BPA) and parabens (PBs), organic chemicals widely used in everyday products, are considered to be endocrine disruptors. We propose a liquid chromatography-tandem mass spectrom...
Cosmetics-triggered percutaneous remote control of transgene expression in mice.Nucleic Acids Res. 43 , e91, (2015)
Synthetic biology has significantly advanced the rational design of trigger-inducible gene switches that program cellular behavior in a reliable and predictable manner. Capitalizing on genetic compone...
Improved sensitivity gas chromatography-mass spectrometry determination of parabens in waters using ionic liquids.Talanta 146 , 568-74, (2015)
A new procedure for the introduction of ionic liquid samples in gas chromatography (GC) is proposed. This procedure, based on microvial insert thermal desorption, allows the direct analysis of the com...