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PU24FCl

Names

[ CAS No. ]:
422508-46-1

[ Name ]:
PU24FCl

Biological Activity

[Description]:

PU24FCl is a specific inhibitor of Hsp90. PU24FCl exhibits wide-ranging anti-cancer activities. PU24FCl accumulates in tumors while being rapidly cleared from normal tissue[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Metabolic Enzyme/Protease >> HSP
Signaling Pathways >> Cell Cycle/DNA Damage >> HSP

[Target]

HSP90


[References]

[1]. Vilenchik M, et, al. Targeting wide-range oncogenic transformation via PU24FCl, a specific inhibitor of tumor Hsp90. Chem Biol. 2004 Jun;11(6):787-97.  

Chemical & Physical Properties

[ Molecular Formula ]:
C20H21ClFN5O3

[ Molecular Weight ]:
433.86400

[ Exact Mass ]:
433.13200

[ PSA ]:
97.31000

[ LogP ]:
3.81220

Related Compounds