Evonimine

Names

[ CAS No. ]:
41758-69-4

[ Name ]:
Evonimine

[Synonym ]:
8α-acetoxy-8-deoxo-evonimine
euonine
ent-(111S,7Ξ)-11β,12β,16α,18β,19β,114-hexaacetoxy-15,11-epoxy-14-hydroxy-7-methyl-(13βH,17βH)-2,9-dioxa-1(12,3)-eudesmana-4(3,2)-pyridina-cyclononaphane-3,8-dione

Biological Activity

[Description]:

Evonimine (Euonine) is an alkaloid isolated from Tripterygium wilfordii Hook. Evonimine exhibits significant inhibition of humoral-mediated immunity using the haemolytic response as an indicator, and shows good anti-feeding activity against the lepidopteran Spodoptera littoralis[1].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Others >> Others

[References]

[1]. Meiqiang Cai, et al. Rapid and sensitive analysis of euonine and wilforidine in human plasma by high-performance liquid chromatography-atmospheric-pressure chemical ionization-mass spectrometry. J Anal Toxicol. 2013 Sep;37(7):395-400.  

Chemical & Physical Properties

[ Melting Point ]:
148-153 °C

[ Molecular Formula ]:
C38H47NO18

[ Molecular Weight ]:
805.77600

[ Exact Mass ]:
805.27900

[ PSA ]:
252.75000

[ LogP ]:
0.86260

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds