Isoglobotriaose

Names

[ CAS No. ]:
41744-59-6

[ Name ]:
Isoglobotriaose

Biological Activity

[Description]:

Isoglobotriaose (Gala-3Galb-4Glc) is a glycosphingolipid found in mammalian tissues. Isoglobotriaose is an analogue of Globotriaose, the ganglioside derivatives of them locate in difference position of small intestine, isoglobotriaosylceramide is restricted to the nonepithelial residue, while globotriaosylceramide is in both compartments[1][2].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Others >> Others

[In Vitro]

Isoglobotriaose is synthesized from lactose, glucose-1-phophate (Glc-1-P), and uridine 5’-triphosphate (UTP) by a one-pot three-enzyme system containing UDP-glucose pyrophosphorylase (GlaU), UDP-Gal 4-epimerase (GalE), and an α1-3galactosytransferase (α1-3GalT)[1].

[References]

[1]. Li W, et al. Strategies for chemoenzymatic synthesis of carbohydrates. Carbohydr Res. 2019 Jan 15;472:86-97. 

[2]. Breimer ME, et al. Glycosphingolipids of rat tissues. Different composition of epithelial and nonepithelial cells of small intestine. J Biol Chem. 1982 Jan 10;257(1):557-68.

Chemical & Physical Properties

[ Molecular Formula ]:
C18H32O16

[ Molecular Weight ]:
504.44

Related Compounds

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