RDR 02308

Names

[ CAS No. ]:
4155-82-2

[ Name ]:
RDR 02308

Biological Activity

[Description]:

RDR 02308 is a TLR4-MyD88 binding inhibitor that inhibits full-length β-lactamase[1].

[Related Catalog]:

Signaling Pathways >> Immunology/Inflammation >> Toll-like Receptor (TLR)

Research Areas >> Inflammation/Immunology

Signaling Pathways >> Anti-infection >> Bacterial

[In Vitro]

RDR 02308 (0-10 μM; 1 h) 在 RAW264.7 细胞中抑制 LPS (HY-D1056) 介导的 IL-6 产生[1]。 Western Blot Analysis[1] Cell Line: RAW264.7 cells Concentration: 0-10 μM Incubation Time: 1 h Result: Inhibited LPS-mediated IL-6 production.

[References]

[1]. Lee HK, et al. Application of beta-lactamase enzyme complementation to the high-throughput screening of toll-like receptor signaling inhibitors. Mol Pharmacol. 2007 Oct;72(4):868-75.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₉H₁₅N₃O₃

[ Molecular Weight ]:
333.34

Related Compounds

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