Diethyl 2,4-pyridinedicarboxylate

Names

[ Name ]:
Diethyl 2,4-pyridinedicarboxylate

[Synonym ]:
2,4-diethylpyridine dicarboxylate
T6NJ BVO2 DVO2
2,4-PDC diethyl ester
Diethyl pyridine-2,4-dicarboxylate
UNII-4SN4572M5S
2,4-pyridinedicarboxylic acid diethyl ester
2,4-Pyridinedicarboxylic acid, diethyl ester
Diethyl 2,4-pyridinedicarboxylate
2,4-diethoxycarbonylpyridine
Diethyl-2,4-pdc
Diethyl 2,4-pyridinedicarboxylic acid
2,4-DPD
Pyridin-2,4-dicarbonsaeure-diaethylester
pyridine-2,4-dicarboxylic acid diethyl ester

Biological Activity

[Description]:

Diethyl pyridine-2,4-dicarb is a potent prolyl 4-hydroxylase-directed proinhibitor. Diethyl pyridine-2,4-dicarb inhibits prolyl hydroxylation and procollagen processing in chick-embryo calvaria[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Tschank G, et al. Inhibition of prolyl hydroxylation and procollagen processing in chick-embryo calvaria by a derivative of pyridine-2,4-dicarboxylate. Characterization of the diethyl ester as a proinhibitor. Biochem J. 1991 Apr 15;275 ( Pt 2)(Pt 2):469-76.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
330.9±22.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₁H₁₃NO₄

[ Molecular Weight ]:
223.23

[ Flash Point ]:
153.9±22.3 °C

[ Exact Mass ]:
223.084457

[ PSA ]:
65.49000

[ LogP ]:
2.00

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.509

Safety Information

[ HS Code ]:
2933399090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%